胰岛素样生长因子系统基因在不同鸭种发育早期肝和肌肉中的表达

doi:10.11843/j.issn.0366-6964.2014.02.003

Abstract

Abstract:

In the present study，expression of IGF-I，IGF type-I receptor (IGF-IR)，and IGF binding protein (IGFBP)-3 genes was quantified by RT-PCR in the liver and muscle tissues on days 13，17，21，25，27 of embryonic development，as well as at 7 days post-hatching (pH) in Gaoyou and Jinding ducks differing in growth rates.The results showed that IGF-I, IGF-IR and IGFBP3 mRNA could be detected as early as on E 13 d in ducks，and showed an extremely significant breed and development differential diathesis.The expression level of IGF-I was very low throughout embryonic development before increasing dramatically by E 27 d and 7 days pH in both duck breeds.In contrast，IGF-I was expressed in muscle at much higher levels than liver throughout development.Expression of liver IGF-IR was higher than that in muscle，and differed between breeds in breast muscle.IGFBP-3 mRNA expression in liver was relatively low in both duck breeds，while in breast muscle increased gradually from the late of the embryonic period to the early post-hatching.Inverse relationships were observed for the expression of IGF-I and IGF-IR，and IGF-I and IGFBP-3，while positive relationship was observed for the expression of IGF-IR and IGFBP-3，meanwhile varying degrees of linear correlation was found between insulin-like growth factor system genes mRNA expression and body weight，liver weight and breast weight in duck.The data indicates differential expression of selected genes that comprise the IGF system in the duck liver tissue during embryonic and early pH growth and development，and provide some data for further study on the mutual regulation mechanism of genes in IGFs system.

CLC Number:

S834.2

SHU Jing-ting，ZHU Wen-qi，SHAN Yan-ju，CHEN Wen-feng，XU Wen-juan，HU Yan，SONG Chi，LI Hui-fang，WANG Jin-yu. Expression of Insulin-like Growth Factor System Genes in Liver and Breast Muscle Tissue during Early Development of Different Duck Breeds[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2014, 45(2): 183-190.

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Expression of Insulin-like Growth Factor System Genes in Liver and Breast Muscle Tissue during Early Development of Different Duck Breeds

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